Understanding SNPs in Weight Management: What You Need to Know

Which SNP associated with weight management is not classified in the known variants?

• A. VDR
• B. ADRB3
• C. FTO
• D. T2DM

Answer: (A)

The SNP associated with weight management that is not classified among the known variants is VDR. This is because VDR (Vitamin D Receptor) gene variants have been studied primarily in the context of vitamin D metabolism and its implications for health, rather than being directly linked to weight management or obesity specifically. In contrast, ADRB3 (Adrenoceptor Beta 3), FTO (Fat Mass and Obesity-associated), and T2DM (Type 2 Diabetes Mellitus) variants have all been recognized and extensively studied in relation to obesity and weight regulation. Each of these genes has been linked to mechanisms influencing fat storage, energy expenditure, and appetite control, making them established players in the genetic landscape of weight management. Therefore, recognizing VDR as an outlier reflects an understanding of how SNPs are classified, with attention given to specific genes that impact weight more directly.

When it comes to the study of genetics and nutrition, one can't help but marvel at the confluence of science and the pursuit of better health. For those gearing up for the Certified Nutrition Specialist (CNS) Practice Exam, understanding Single Nucleotide Polymorphisms (SNPs) associated with weight management is crucial. But let’s dig in deeper—not every SNP you've read about fits neatly into the category of specifically weight-related genes. Have you ever heard the term VDR? If not, you’re in for an enlightening discussion.